Is your memory as good as it was when you were younger? The answer is probably not. We all lose a little as we age, but what if there was something natural you could drink that could restore your memory to what it was 10 or 20 years ago? CBS 2′s Dr. Max Gomez reports on the memory breakthrough.
The governors of a number of states, including New York and New Jersey, recently imposed 21-day quarantines on health care workers returning to the United States from regions of the world where they may have cared for patients with Ebola virus disease. We understand their motivation for this policy — to protect the citizens of their states from contracting this often-fatal illness. This approach, however, is not scientifically based, is unfair and unwise, and will impede essential efforts to stop these awful outbreaks of Ebola disease at their source, which is the only satisfactory goal. The governors’ action is like driving a carpet tack with a sledgehammer: it gets the job done but overall is more destructive than beneficial.
As faculty members at Columbia University, we write in support of our colleague Dr. Craig Spencer, as well as all other health care workers returning from Ebola-stricken regions and treating Ebola here in the United States.
Dr. Bassett and her two siblings grew up attending antiwar and antiracism demonstrations, reading James Baldwin books and were pushed to be free thinkers, their mother said. She graduated from Harvard University and ran a sickle-cell anemia clinic before moving back to New York to attend Columbia University’s medical school, where she did her residency in nearby Central Harlem.
Dr. Abdul El-Sayed, assistant professor of epidemiology at Columbia University’s Mailman School of Public Health, talks to Roseanne Colletti about the recent news surrounding the Ebola epidemic.
In a small study in the journal Nature Neuroscience, healthy people, ages 50 to 69, who drank a mixture high in antioxidants called cocoa flavanols for three months performed better on a memory test than people who drank a low-flavanol mixture. On average, the improvement of high-flavanol drinkers meant they performed like people two to three decades younger on the study’s memory task, said Dr. Scott A. Small, a neurologist at Columbia University Medical Center and the study’s senior author. They performed about 25 percent better than the low-flavanol group.
Scott Small, a professor of neurology at Columbia University’s College of Physicians and Surgeons, researches Alzheimer’s, but he also studies the memory loss that occurs during the normal aging process. Research on the commonplace “senior moments” focuses on the hippocampus, an area of the brain involved with formation of new memories. In particular, one area of the hippocampus, the dentate gyrus, which helps distinguish one object from another, has lured researchers on age-related memory problems.
“Human beings come in many different sizes and have different preexisting conditions that may put them at higher risk,” says Robert Whittington, professor of clinical anesthesiology at Columbia University Medical Center.
“We could use a strategy similar to the ring vaccination strategy that was used in the smallpox eradication program,” says Stephen Morse, an epidemiologist at Columbia University’s Mailman School of Public Health.
“There’s no proven benefit to robotic surgery, and it’s significantly more costly,” said the lead author, Dr. Jason D. Wright, director of gynecological oncology at Columbia University Medical Center.
“At most it will have a very modest effect on food intake,” says Marie-Pierre St-Onge, assistant professor of nutritional medicine at Columbia University Medical Center in New York.
Aside from four people who shared an apartment with Duncan in the early days of his illness, the U.S. government has kept all quarantines voluntary. The fact that those four did not fall ill despite their exposure shows that casual contact, such as sharing an airplane, with someone before they are significantly symptomatic carries very little risk, said Amy Fairchild, a professor of sociomedical sciences at Columbia University’s Mailman School of Public Health in New York City.
Dr. W. Ian Lipkin, an epidemiology professor at Columbia University’s Mailman School of Public Health and one of the world’s leading infectious-disease investigators, was on his way to a meeting on campus last Wednesday. He would have preferred to be in West Africa.
Ms. Chavez, 18 years old, did end up at Columbia—as one of 34 Thompson-Muñoz scholars, beneficiaries of a new grant program the university has created exclusively for students who grew up or went to school in the area surrounding Columbia and its new campus currently under construction in the West Harlem neighborhood of Manhattanville.
Stephen Morse, a professor of epidemiology at Columbia University’s Mailman School of Public Health, told me: “We have a lot of vaccine-preventable diseases and we see more and more people refusing to have their children take vaccines.”
Karen Duff, an Alzheimer’s researcher at Columbia University, while praising the work as “a tour de force,” cautioned that once Alzheimer’s starts, tangles can take off on their own and may need to be attacked by drugs that strike them specifically in order to stop devastation in the brain.
There is a fourth strategy, although it will need to be evaluated and deployed carefully. Since the 1990s, novel methods have allowed doctors to detect viruses in the pre-symptomatic phase of an infection, often with remarkable sensitivity and precision. One of these involves the polymerase chain reaction, or P.C.R., a chemical reaction that amplifies pieces of a virus’s genes floating in blood by more than a millionfold, which is what makes early, pre-symptomatic infections identifiable.
Dieter Egli, assistant professor in the pediatrics department at Columbia University Medical Center, said his laboratory will try to repeat Melton’s experiment immediately. “It’s a wonderful result, something we’ve been waiting for quite awhile,” Egli said.
Dr. Emile Bacha explains the procedure that resulted in a 3-D printed heart saving the life of a two-week old baby.
In the latest study to question the value of robotic surgery, researchers from Columbia University found that the technology costs significantly more and has a higher rate of complications than regular minimally invasive surgery for removing ovaries and ovarian cysts.
If the Transeuro trial shows that patients gain improvements after the transplant with reduced side effects, “there’s a future for stem cells” with the disease, says Stanley Fahn, a neurology professor at Columbia University in New York who was the co-primary investigator on one of the two National Institutes of Health-funded transplant trials in the 1990s.
Columbia University professor of neuroscience and Nobelist Eric Kandel told CBS News in an email, “This year’s Nobel Prize in Physiology or Medicine recognizes an extraordinary set of contributions to brain science.” The work of the three scientists “has illuminated the neural computation underlying a complex cognitive function: position in space – the first cognitive function we understand on the cellular level.”
A British-American scientist and a pair of Norwegian researchers were awarded this year’s Nobel Prize in Physiology or Medicine on Monday for discovering “an inner GPS, in the brain,” that makes navigation possible for virtually all creatures. John O’Keefe, 75, a British-American scientist, will share half of the prize of 8 million kronor, or $1.1 million, in what is considered the most prestigious scientific award. May-Britt Moser, 51, and Edvard I. Moser, 52, who are married, will share the other half, said the Karolinska Institute in Sweden, which chooses the laureates. …The three also won Columbia University’s Louisa Gross Horwitz Prize last year for their discoveries.
A U.S.-British scientist and a Norwegian husband-and-wife research team won the Nobel Prize in medicine Monday for discovering the brain’s navigation system — the inner GPS that helps us find our way in the world — a revelation that could lead to advances in diagnosing Alzheimer’s. The research by John O’Keefe, May-Britt Moser and Edvard Moser represents a “paradigm shift” in neuroscience that could help researchers understand the sometimes severe spatial memory loss associated with Alzheimer’s disease, the Nobel Assembly said. …All three Nobel laureates won Columbia University’s Louisa Gross Horwitz Prize last year for their discoveries. They will split the Nobel prize money of 8 million Swedish kronor (about $1.1 million), with half to O’Keefe and the other half to the Mosers.
The worst day of Kenneth Olive’s career began unremarkably. He woke up in his two-bedroom apartment in Harlem and tag-teamed breakfast for his 1-year-old son as he and his wife raced to get ready for work. At the 116th Street subway stop nearby, Olive hopped on a C train uptown to 168th Street. His lab is about a block away, in the cancer center at the heart of Columbia University’s medical complex.
“If it were universally adopted, that would be a great thing because we would have far fewer people at risk for unintended pregnancy,” said Dr. Irwin Redlener, the president of the Children’s Health Fund and a pediatrics professor at Columbia University, who was not involved with the research or the guidelines.
“From now on, it will be hard for anyone to continue to recommend the introduction of gluten specifically at the age of 4 to 6 months,” the timetable tested in one of the studies, according to an accompanying editorial by Drs. Jonas Ludvigsson of the Karolinska Institute in Stockholm and Peter Green of the Columbia University College of Physicians and Surgeons in New York City.
“The Sunshine Act is a watershed moment,” said Susan Chimonas, associate director of research at Columbia University’s Center on Medicine as a Profession. “It’s a tantalizing first look at what kind of industry ties doctors have.”
Cardiologists should discuss with patients the risks and benefits of chest imaging using ionizing radiation before the procedure, according to a new statement endorsed by several medical organizations. Ionizing radiation, which can come from cardiac stress tests, CT scans and certain heart procedures, is tied to increased cancer risk. “There is continuing concern on the part of patients in the area of ionizing radiation,” said Dr. Andrew J. Einstein, an associate professor of medicine in radiology at Columbia University in New York.
Low-carb diets have been advocated by various “experts” for at least 225 years. Many sources credit John Rollo with being the first to promote a low carbohydrate diet for diabetics in the late 1700s. In the 1860s, an English undertaker by the name of Banting published his famous “Letter on Corpulence, Addressed to the Public.” His diet, which advocated giving up several starchy foods, was so popular that for decades dieting was actually called “Banting.”
The newest addition to Columbia University is also the most fun to watch rise. The new home for Columbia University Medical Center’s graduate program is a crazy zig-zagging tower with a “study cascade” designed by Diller Scofidio + Renfro.
“It’s assumed that the prenatal period is going to be your most susceptible period [for disease], including lung development,” says Robin Whyatt, a study co-author and a professor of environmental health sciences at Columbia’s Mailman School of Public Health. The researchers cautioned that while the study found an association between phthalates and asthma, it didn’t prove causation.
Featuring interviews with renowned alumni, the film reveals a rare and intimate portrait of one of the world’s leading research universities whose history and character is inextricably linked with that of New York City itself.
“For me, this is the big one.” Gervasio Lamas, the chief of Columbia University’s cardiology division at Mount Sinai Medical Center in Miami Beach, took out his phone and tapped the battery. “Cadmium. This thing ends up in the dump in West Palm Beach, and then I end up drinking it.”
Researchers say they have discovered a way to diagnose depression from a simple blood test. Dr. Jeffrey Lieberman, chief of psychiatry at Columbia University, joins the “CBS This Morning” co-hosts to discuss the potential breakthrough.
A research team from Columbia University followed a group of 300 moms and children in New York’s inner city for several years. Researchers compared the urine tests of the mothers’ during pregnancy—testing for concentrations of phthalates—to whether their children had asthma at ages 5-11.
Another Midas participant, Jeffrey L. Shaman, an associate professor of environmental health sciences at the Columbia University Mailman School of Public Health, agreed. “Ebola has a simple trajectory because it’s growing exponentially,” Dr. Shaman said.
Geneticist Wendy Chung describes what it’s like to chip away at the mysteries of autism, and the excitement of uncovering tiny but critical clues.
A “mystery shopper” experiment set up by Columbia University’s Mailman School of Public Health and Columbia University Medical Center showed that 20% of men weren’t able to buy emergency contraception after explaining to a pharmacist that the condom they used broke. And almost three-quarters of pharmacies studied made it difficult for men to get the pills, which block ovulation. The study was published in the October issue of the journal Contraception.
What can we do? In June of 2013, the American Medical Association finally recognized obesity as a disease affecting more than one-third of U.S. adults. This is still not reaching enough people though. Only 25 percent of doctors are comfortable even discussing nutrition with their patients, and almost 30 percent say that no one in their practice is trained to deal with weight-related issues.
Dr. Michael Rosenbaum is a professor of pediatrics and medicine at Columbia University Medical Center.
CBS 2′s Dr. Max Gomez says a gene discovery could bring researchers a step closer to diagnosing kids born at risk for celiac disease.
Nonetheless, in an accompanying editorial, David Rothman, who directs the Center for the Study of Society and Medicine at the Columbia University Medical Center, writes that “caution is still in order, since the FDA insists that its need for expertise may outweigh the risk of conflicts of interest, thereby ignoring the option of allowing experts to testify, but not to vote.”
The findings bolster the mainstream view that the ancestors of European Jews were people from the Levant and local Europeans, said study researcher Itsik Pe’er, an associate professor of computer science and systems biology at Columbia University.
GARY SCHWARTZ: The holy grail of oncology has been to try to develop a test, either in the blood or the urine or some bodily fluid that would allow us to detect cancer at an early stage.
EMILY SENAY: Doctor Gary Schwartz is the head of oncology and hematology at Columbia University Medical Center. He’s impressed by the results from the Italian study- but has some doubts about the 98% detection rate.
GARY SCHWARTZ: I am a little skeptical on the outcome reported in this particular abstract from the Milan group.
Certain to launch a volley of passionate praise and vitriolic criticism, the study is a groundbreaking collaboration between husband and wife Eric and Denise Kandel that combines epidemiology, psychology, and molecular biology. Pointing to a body of previous epidemiological research demonstrating that nicotine is a gateway for marijuana and cocaine use, the Kandels argue that e-cigarettes, by introducing nonsmoking kids to nicotine, extend that gateway. To back up the accusation, they marshal biological data on the effects of nicotine in the brains of mice, and psychological studies into the processes of addiction.
If we can understand the basic immune system, what turns it on and turns it off and how to release it in a way that attacks the cancer cells specifically, that would be considered a major advance in oncology.
Gary Schwartz, MD is professor of medicine at Columbia University Medical Center.
CBS 2′s Dr. Max Gomez has more on some of the latest developments in breast cancer research.
Nicotine — whether it comes from a traditional or electronic cigarette — could be a gateway drug to marijuana and cocaine, according to a study in the New England Journal of Medicine. “While e-cigarettes do eliminate some of the health effects associated with combustible tobacco, they are pure nicotine-delivery devices,” said co-author Dr. Denise B. Kandel, a professor of sociomedical sciences at Columbia University Medical Center and a research scientist at the New York State Psychiatric Institute.