A new study finds that regulatory gene variants can affect the severity of a genetic disease among people with the same protein-coding mutation.
Studies answer an old debate in developmental biology: How do cells destined to form a particular tissue or structure remember what they're supposed to be?
Solving a 60-year-old medical mystery, a team led by Columbia researchers has discovered what causes kidney and urinary tract defects in people with DiGeorge syndrome.
The 2016 Horwitz Prize winners studied how molecules can regulate the structure, behavior, and activity of DNA without modifying its genetic code.
Expanded prenatal genetic testing may increase the detection of carriers for a variety of potentially serious conditions.
When injected into older animals, a hormone made by the skeleton of young animals dramatically improves exercise capacity, a new Columbia study finds.